FASCINATION ABOUT CONOLIDINE ALKALOID FOR CHRONIC PAIN

Most not too long ago, it has been recognized that conolidine and the above derivatives act around the atypical chemokine receptor three (ACKR3. Expressed in equivalent parts as classical opioid receptors, it binds to a wide array of endogenous opioids. Unlike most opioid receptors, this receptor acts like a scavenger and does not activate a second